BDBM50299193 CHEMBL573656::N-benzyl-1-(4-((2-chloro-5-(5-(methylsulfonyl)-1-(3-morpholinopropyl)-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridin-3-yl)phenyl)ethynyl)phenyl)-N-methylmethanamine

SMILES CN(Cc1ccccc1)Cc1ccc(cc1)C#Cc1cc(ccc1Cl)-c1nn(CCCN2CCOCC2)c2CCN(Cc12)S(C)(=O)=O

InChI Key InChIKey=CXCDLXPYSUCCLQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50299193   

TargetCathepsin S(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50299193(CHEMBL573656 | N-benzyl-1-(4-((2-chloro-5-(5-(meth...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of cathepsin S in human JY cells assessed as invariant chain li degradation by western blottingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50299193(CHEMBL573656 | N-benzyl-1-(4-((2-chloro-5-(5-(meth...)
Affinity DataIC50:  600nMAssay Description:Inhibition of human recombinant cathepsin S expressed in baculovirus by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed