BDBM50299196 CHEMBL573657::N-(4-((2-chloro-5-(5-(methylsulfonyl)-1-(3-morpholinopropyl)-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridin-3-yl)phenyl)ethynyl)benzyl)-1-(4-methoxyphenyl)methanamine

SMILES COc1ccc(CNCc2ccc(cc2)C#Cc2cc(ccc2Cl)-c2nn(CCCN3CCOCC3)c3CCN(Cc23)S(C)(=O)=O)cc1

InChI Key InChIKey=RDBXEODYTOMMBB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50299196   

TargetCathepsin S(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50299196(CHEMBL573657 | N-(4-((2-chloro-5-(5-(methylsulfony...)
Affinity DataIC50:  820nMAssay Description:Inhibition of cathepsin S in human JY cells assessed as invariant chain li degradation by western blottingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50299196(CHEMBL573657 | N-(4-((2-chloro-5-(5-(methylsulfony...)
Affinity DataIC50:  230nMAssay Description:Inhibition of human recombinant cathepsin S expressed in baculovirus by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed