BDBM50299204 (S)-1-(1'-(3-(3-(4-chloro-3-((4-chlorophenyl)ethynyl)phenyl)-5-(methylsulfonyl)-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridin-1-yl)-2-hydroxypropyl)-4,4'-bipiperidin-1-yl)ethanone::CHEMBL583129
SMILES CC(=O)N1CCC(CC1)C1CCN(C[C@H](O)Cn2nc(c3CN(CCc23)S(C)(=O)=O)-c2ccc(Cl)c(c2)C#Cc2ccc(Cl)cc2)CC1
InChI Key InChIKey=YWTPUEVGTJTTOF-YTTGMZPUSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50299204
TargetCathepsin S(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of cathepsin S in human JY cells assessed as invariant chain li degradation by western blottingMore data for this Ligand-Target Pair
TargetCathepsin S(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Inhibition of human recombinant cathepsin S expressed in baculovirus by FRET assayMore data for this Ligand-Target Pair