BDBM50299782 1-(2-((2,3-difluorophenoxy)methyl)phenyl)piperazine::CHEMBL575714

SMILES Fc1cccc(OCc2ccccc2N2CCNCC2)c1F

InChI Key InChIKey=KETAEAPLSWORIE-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50299782   

TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50299782(1-(2-((2,3-difluorophenoxy)methyl)phenyl)piperazin...)
Affinity DataKi:  80nMAssay Description:Displacement of [125I]RTI-55 from human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50299782(1-(2-((2,3-difluorophenoxy)methyl)phenyl)piperazin...)
Affinity DataKi:  101nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50299782(1-(2-((2,3-difluorophenoxy)methyl)phenyl)piperazin...)
Affinity DataKi:  470nMAssay Description:Displacement of [125I]RTI-55 from human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50299782(1-(2-((2,3-difluorophenoxy)methyl)phenyl)piperazin...)
Affinity DataKi:  781nMAssay Description:Displacement of [125I]RTI-55 from human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed