BDBM50300052 5-(4-Methylbenzyl)-7,12-dihydroindolo[3,2-d][1]benzazepin-6(5H)-one::CHEMBL572923

SMILES Cc1ccc(CN2c3ccccc3-c3[nH]c4ccccc4c3CC2=O)cc1

InChI Key InChIKey=PSPWZGBZRWYJLW-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50300052   

TargetMalate dehydrogenase, mitochondrial(Homo sapiens (Human))
Technische Universit£T Braunschweig

Curated by ChEMBL
LigandPNGBDBM50300052(5-(4-Methylbenzyl)-7,12-dihydroindolo[3,2-d][1]ben...)
Affinity DataIC50:  1.05E+4nMAssay Description:Inhibition of mitochondrial malate dehydrogenase by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Technische Universit£T Braunschweig

Curated by ChEMBL
LigandPNGBDBM50300052(5-(4-Methylbenzyl)-7,12-dihydroindolo[3,2-d][1]ben...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of GSK3-betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50300052(5-(4-Methylbenzyl)-7,12-dihydroindolo[3,2-d][1]ben...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CDK1/cyclin BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed