BDBM50300993 (2S,3S,4S,5R,6S)-6-{4-[(2S,3R)-3-[(3S)-3-(4-fluorophenyl)-3-hydroxypropyl]-1-(2-hydrogeniophenyl)-4-oxoazetidin-2-yl]-2-hydrogeniophenoxy}-3,4,5-trihydroxyoxane-2-carboxylic acid::CHEMBL578401

SMILES O[C@@H](CC[C@@H]1[C@H](N(C1=O)c1ccccc1)c1ccc(O[C@@H]2O[C@@H]([C@@H](O)[C@H](O)[C@H]2O)C(O)=O)cc1)c1ccc(F)cc1

InChI Key InChIKey=QVUSMROKGZCDDR-ADEYADIWSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50300993   

TargetNPC1-like intracellular cholesterol transporter 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50300993((2S,3S,4S,5R,6S)-6-{4-[(2S,3R)-3-[(3S)-3-(4-fluoro...)
Affinity DataIC50:  200nMAssay Description:Displacement of [35S](2S,3S,4S,5R,6S)-6-(4-((2S,3R)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-1-(4-(3-(methylsulfonamido)prop-1-ynyl)phenyl)-4-oxoaz...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNPC1-like intracellular cholesterol transporter 1(Rattus norvegicus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50300993((2S,3S,4S,5R,6S)-6-{4-[(2S,3R)-3-[(3S)-3-(4-fluoro...)
Affinity DataIC50:  127nMAssay Description:Displacement of [35S](2S,3S,4S,5R,6S)-6-(4-((2S,3R)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-1-(4-(3-(methylsulfonamido)prop-1-ynyl)phenyl)-4-oxoaz...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNPC1-like intracellular cholesterol transporter 1(Mus musculus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50300993((2S,3S,4S,5R,6S)-6-{4-[(2S,3R)-3-[(3S)-3-(4-fluoro...)
Affinity DataIC50:  1.20E+3nMAssay Description:Displacement of [35S](2S,3S,4S,5R,6S)-6-(4-((2S,3R)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-1-(4-(3-(methylsulfonamido)prop-1-ynyl)phenyl)-4-oxoaz...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNPC1-like intracellular cholesterol transporter 1(Rattus norvegicus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50300993((2S,3S,4S,5R,6S)-6-{4-[(2S,3R)-3-[(3S)-3-(4-fluoro...)
Affinity DataIC50:  173nMAssay Description:Displacement of [35S](2S,3S,4S,5R,6S)-6-(4-((2S,3R)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-1-(4-(3-(methylsulfonamido)prop-1-ynyl)phenyl)-4-oxoaz...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNPC1-like intracellular cholesterol transporter 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50300993((2S,3S,4S,5R,6S)-6-{4-[(2S,3R)-3-[(3S)-3-(4-fluoro...)
Affinity DataIC50:  150nMAssay Description:Displacement of [35S](2S,3S,4S,5R,6S)-6-(4-((2S,3R)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-1-(4-(3-(methylsulfonamido)prop-1-ynyl)phenyl)-4-oxoaz...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed