BDBM50302402 7-bromo-2-(2-chloro-6-fluorophenyl)-1H-phenanthro[9,10-d]imidazole::CHEMBL566261
SMILES Fc1cccc(Cl)c1-c1nc2c([nH]1)c1cccc(Br)c1c1ccccc21
InChI Key InChIKey=KLDPORRVVYLMRJ-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50302402
TargetProstaglandin E synthase(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Displacement of [3H]PGH2 from human recombinant PGES1 expressed in CHOK1 cellsMore data for this Ligand-Target Pair
TargetProstaglandin E synthase(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of mPGES1 in IL-1beta-stimulated human A549 cells assessed as blockade of PGH2 to PGE2 conversion in presence of 50% fetal bovine serumMore data for this Ligand-Target Pair