BDBM50302781 (R)-(8-oxo-2-phenethyl-2,4,5,6,7,8-hexahydropyrazolo[4,3-e][1,4]diazepin-6-yl)methyl isoquinoline-5-carboxylate::CHEMBL570672

SMILES O=C(OC[C@H]1CNc2cn(CCc3ccccc3)nc2C(=O)N1)c1cccc2cnccc12

InChI Key InChIKey=GNQLTIMVDQALEW-LJQANCHMSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50302781   

TargetP2X purinoceptor 7(Homo sapiens (Human))
Institute Of Science & Technology

Curated by ChEMBL
LigandPNGBDBM50302781((R)-(8-oxo-2-phenethyl-2,4,5,6,7,8-hexahydropyrazo...)
Affinity DataIC50:  790nMAssay Description:Antagonist activity at human P2X7 receptor expressed in HEK293 cells assessed as inhibition of BzATP-induced fluorescent ethidium accumulation at 10 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed