BDBM50303040 4-(methyl(4-(5-methylthiophen-2-yl)pyrimidin-2-yl)amino)benzenesulfonamide::CHEMBL571525

SMILES CN(c1ccc(cc1)S(N)(=O)=O)c1nccc(n1)-c1ccc(C)s1

InChI Key InChIKey=XWOIYAXPTUFYIP-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50303040   

TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50303040(4-(methyl(4-(5-methylthiophen-2-yl)pyrimidin-2-yl)...)
Affinity DataIC50:  6.50E+4nMAssay Description:Inhibition of GSK3betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDickkopf-related protein 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50303040(4-(methyl(4-(5-methylthiophen-2-yl)pyrimidin-2-yl)...)
Affinity DataEC50:  9.80E+3nMAssay Description:Inhibition of Dkk1-mediated Wnt/beta-catenin signaling in osteosasrcoma cells assessed as potentiation of TCF-luciferase responseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed