BDBM50303592 CHEMBL568756::N-(4-(4-(3-(3-tert-butyl-1-m-tolyl-1H-pyrazol-5-yl)ureido)phenylamino)quinolin-6-yl)propionamide

SMILES CCC(=O)Nc1ccc2nccc(Nc3ccc(NC(=O)Nc4cc(nn4-c4cccc(C)c4)C(C)(C)C)cc3)c2c1

InChI Key InChIKey=KDPYXTRRUCHGKB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50303592   

TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Chemical Genomics Centre Of The Max Planck Society

Curated by ChEMBL
LigandPNGBDBM50303592(CHEMBL568756 | N-(4-(4-(3-(3-tert-butyl-1-m-tolyl-...)
Affinity DataIC50:  420nMAssay Description:Displacemnt of N,N'-(2,2'-(3,3'-disulfanediylbis(2,5-dioxopyrrolidine-3,1-diyl))bis(ethane-2,1-diyl))bis(2-(3-(3-tert-butyl-5-(3-naphthalen-1-ylureid...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Chemical Genomics Centre Of The Max Planck Society

Curated by ChEMBL
LigandPNGBDBM50303592(CHEMBL568756 | N-(4-(4-(3-(3-tert-butyl-1-m-tolyl-...)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibition of p38alpha active form expressed in Escherichia coli BL21(DE3) cells by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed