BDBM50303631 CHEMBL571560::N-Benzyl-17-(cyclobutylmethyl)morphinan-3-amine

SMILES C(Nc1ccc2C[C@@H]3[C@@H]4CCCC[C@]4(CCN3CC3CCC3)c2c1)c1ccccc1

InChI Key InChIKey=WFGYABIAABXTFI-KJYTXNCISA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50303631   

TargetMu-type opioid receptor(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50303631(CHEMBL571560 | N-Benzyl-17-(cyclobutylmethyl)morph...)
Affinity DataKi:  1.70nMAssay Description:Displacement of [3H]-DAMGO from human mu opioid receptor expressed in CHO cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50303631(CHEMBL571560 | N-Benzyl-17-(cyclobutylmethyl)morph...)
Affinity DataKi:  1.70nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50303631(CHEMBL571560 | N-Benzyl-17-(cyclobutylmethyl)morph...)
Affinity DataKi:  2.80nMAssay Description:Displacement of [3H]-U69,593 from human kappa opioid receptor expressed in CHO cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50303631(CHEMBL571560 | N-Benzyl-17-(cyclobutylmethyl)morph...)
Affinity DataKi:  2.80nMAssay Description:Displacement of [3H]U69593 from human kappa opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50303631(CHEMBL571560 | N-Benzyl-17-(cyclobutylmethyl)morph...)
Affinity DataKi:  130nMAssay Description:Displacement of [3H]naltrindole from human delta opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50303631(CHEMBL571560 | N-Benzyl-17-(cyclobutylmethyl)morph...)
Affinity DataKi:  130nMAssay Description:Displacement of [3H]-naltrindole from human delta opioid receptor expressed in CHO cells after 3 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed