BDBM50303649 4-{(S)-2-[4-(4-Chlorophenoxy)phenoxymethyl]pyrrolidin-1-yl}-butyric Acid::CHEMBL565789
SMILES OC(=O)CCCN1CCC[C@H]1COc1ccc(Oc2ccc(Cl)cc2)cc1
InChI Key InChIKey=PVCTYSQBVIGZRU-KRWDZBQOSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50303649
Affinity DataIC50: 47nMAssay Description:Inhibition of human recombinant LTA4H hydrolysis assessed as inhibition of LTB4 formation by LC-MS/MSChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataIC50: 37nMAssay Description:Inhibition of human LTA4H hydrolysis assessed as inhibition of Ca2+ ionophore-stimulated LTB4 formation in human whole blood by ELISAChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataIC50: 54nMAssay Description:Inhibition of recombinant full length N-terminal His6-tagged LTA4H (unknown origin) expressed in Escherichia coli BL21 DE3 cells at enzyme concentrat...More data for this Ligand-Target Pair
Affinity DataIC50: 510nMAssay Description:Inhibition of LTA4H in human whole blood assessed as reduction of calcium ionophore A23187-stimulated LTB4 generation preincubated for 4 hrs followed...More data for this Ligand-Target Pair
Affinity DataIC50: 74nMAssay Description:Inhibition of LTA4H in human PBMC assessed as reduction of calcium ionophore A23187-stimulated LTB4 generation preincubated for 4 hrs followed by ion...More data for this Ligand-Target Pair
Affinity DataKd: 25nMAssay Description:Binding affinity to human recombinant LTA4H by isothermal calorimetryChecked by AuthorMore data for this Ligand-Target Pair