BDBM50303801 CHEMBL571546::N-benzyl-2-(5-(4-(2-morpholinoethoxy)phenyl)pyridin-2-yl)acetamide

SMILES O=C(Cc1ccc(cn1)-c1ccc(OCCN2CCOCC2)cc1)NCc1ccccc1

InChI Key InChIKey=HUNGUWOZPQBXGX-UHFFFAOYSA-N

Data  8 IC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50303801   

TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50303801(CHEMBL571546 | N-benzyl-2-(5-(4-(2-morpholinoethox...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of src kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50303801(CHEMBL571546 | N-benzyl-2-(5-(4-(2-morpholinoethox...)
Affinity DataIC50:  20nMAssay Description:Inhibition of c-SRCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50303801(CHEMBL571546 | N-benzyl-2-(5-(4-(2-morpholinoethox...)
Affinity DataIC50:  4.00E+4nMAssay Description:Inhibition of src kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
Athenex

Curated by ChEMBL
LigandPNGBDBM50303801(CHEMBL571546 | N-benzyl-2-(5-(4-(2-morpholinoethox...)
Affinity DataIC50:  100nMAssay Description:Inhibition of BCR/ABL (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50303801(CHEMBL571546 | N-benzyl-2-(5-(4-(2-morpholinoethox...)
Affinity DataIC50:  13nMAssay Description:Inhibition of human c-SRC expressed in mouse NIH/3T3 cells assessed as inhibition of cell growth in presence of 1.5% FCS by BrdU incorporation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50303801(CHEMBL571546 | N-benzyl-2-(5-(4-(2-morpholinoethox...)
Affinity DataIC50:  6.5nMAssay Description:Inhibition of human c-SRC expressed in mouse NIH/3T3 cells assessed as inhibition of cell growth in presence of 0.5% FCSMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lyn(Homo sapiens (Human))
Athenex

Curated by ChEMBL
LigandPNGBDBM50303801(CHEMBL571546 | N-benzyl-2-(5-(4-(2-morpholinoethox...)
Affinity DataIC50:  100nMAssay Description:Inhibition of LYN (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50303801(CHEMBL571546 | N-benzyl-2-(5-(4-(2-morpholinoethox...)
Affinity DataIC50:  6.70E+4nMAssay Description:Inhibition of Src (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed