BDBM50304058 1,3-Di[3-(4-thiophene-3-yl-phenyl)tropane-2-carbonylaminomethyl]benzene::CHEMBL607548

SMILES CN1C2CCC1[C@@H]([C@H](C2)c1ccc(cc1)-c1ccsc1)C(=O)NCc1cccc(CNC(=O)[C@@H]2C3CCC(C[C@@H]2c2ccc(cc2)-c2ccsc2)N3C)c1

InChI Key InChIKey=RLTILGBQVNXKRQ-DDZGMJBXSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50304058   

TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Aarhus University

Curated by ChEMBL
LigandPNGBDBM50304058(1,3-Di[3-(4-thiophene-3-yl-phenyl)tropane-2-carbon...)
Affinity DataKi:  230nMAssay Description:Displacement of [125I]methyl 3-(4-iodophenyl)-8-methyl-8-aza-bicyclo[3.2.1]octane-2-carboxylate from human recombinant DAT expressed in african green...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Aarhus University

Curated by ChEMBL
LigandPNGBDBM50304058(1,3-Di[3-(4-thiophene-3-yl-phenyl)tropane-2-carbon...)
Affinity DataKi:  860nMAssay Description:Displacement of [125I]methyl 3-(4-iodophenyl)-8-methyl-8-aza-bicyclo[3.2.1]octane-2-carboxylate from human recombinant SERT expressed in african gree...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Aarhus University

Curated by ChEMBL
LigandPNGBDBM50304058(1,3-Di[3-(4-thiophene-3-yl-phenyl)tropane-2-carbon...)
Affinity DataKi:  1.20E+3nMAssay Description:Displacement of [125I]methyl 3-(4-iodophenyl)-8-methyl-8-aza-bicyclo[3.2.1]octane-2-carboxylate from human recombinant NET expressed in african green...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed