BDBM50304170 17-Cyclopropylmethyl-3,14beta-dihydroxy-4,5alpha-epoxy-6beta-[(4'-bromo)benzamido]morphinan-oxalate::CHEMBL611930::[14C]-17-Cyclopropylmethyl-3,14beta-dihydroxy-4,5alpha-epoxy-6beta-[(4'-bromo)benzamido]morphinan-oxalate
SMILES Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)[C@@H](CC[C@@]35O)NC(=O)c1ccc(Br)cc1
InChI Key InChIKey=XEQUQWJVHIEWQA-XGTKUTNFSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 15 hits for monomerid = 50304170
TargetKappa-type opioid receptor(Homo sapiens (Human))
Human Biomolecular Research Institute
Curated by ChEMBL
Human Biomolecular Research Institute
Curated by ChEMBL
Affinity DataKi: 0nMAssay Description:Antagonist activity at kappa opioid receptor expressed in HEK293 cells assessed as inhibition of compound 16-induced [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Homo sapiens (Human))
Human Biomolecular Research Institute
Curated by ChEMBL
Human Biomolecular Research Institute
Curated by ChEMBL
Affinity DataKi: 0.290nMAssay Description:Displacement of [3H]U69593 from kappa opioid receptor expressed in HEK293 cells by visible spectrophotometryMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Homo sapiens (Human))
Human Biomolecular Research Institute
Curated by ChEMBL
Human Biomolecular Research Institute
Curated by ChEMBL
Affinity DataKi: 0.880nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor expressed in HEK293 cells by visible spectrophotometryMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Homo sapiens (Human))
Human Biomolecular Research Institute
Curated by ChEMBL
Human Biomolecular Research Institute
Curated by ChEMBL
Affinity DataKi: 2.20nMAssay Description:Displacement of [3H]DPDPE from delta opioid receptor expressed in HEK293 cells by visible spectrophotometryMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Homo sapiens (Human))
Human Biomolecular Research Institute
Curated by ChEMBL
Human Biomolecular Research Institute
Curated by ChEMBL
Affinity DataKi: >10nMAssay Description:Antagonist activity at delta opioid receptor expressed in HEK293 cells assessed as inhibition of compound 14-induced [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Homo sapiens (Human))
Human Biomolecular Research Institute
Curated by ChEMBL
Human Biomolecular Research Institute
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:Antagonist activity at mu opioid receptor expressed in HEK293 cells assessed as inhibition of compound 11-induced [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
TargetNociceptin receptor(Homo sapiens (Human))
Human Biomolecular Research Institute
Curated by ChEMBL
Human Biomolecular Research Institute
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:Antagonist activity at NOP expressed in HEK293 cells assessed as inhibition of compound 15-induced [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
TargetNociceptin receptor(Homo sapiens (Human))
Human Biomolecular Research Institute
Curated by ChEMBL
Human Biomolecular Research Institute
Curated by ChEMBL
Affinity DataEC50: >1.00E+4nMAssay Description:Activity at NOP expressed in HEK293 cells assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Homo sapiens (Human))
Human Biomolecular Research Institute
Curated by ChEMBL
Human Biomolecular Research Institute
Curated by ChEMBL
Affinity DataEC50: 66nMAssay Description:Inverse agonist activity at delta opioid receptor expressed in HEK293 cells assessed as inhibition of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Homo sapiens (Human))
Human Biomolecular Research Institute
Curated by ChEMBL
Human Biomolecular Research Institute
Curated by ChEMBL
Affinity DataEC50: 0.100nMAssay Description:Activity at kappa opioid receptor expressed in HEK293 cells assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Homo sapiens (Human))
Human Biomolecular Research Institute
Curated by ChEMBL
Human Biomolecular Research Institute
Curated by ChEMBL
Affinity DataEC50: 0.200nMAssay Description:Activity at delta opioid receptor expressed in HEK293 cells assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Homo sapiens (Human))
Human Biomolecular Research Institute
Curated by ChEMBL
Human Biomolecular Research Institute
Curated by ChEMBL
Affinity DataEC50: >1.00E+4nMAssay Description:Inverse agonist activity at mu opioid receptor expressed in HEK293 cells assessed as inhibition of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Homo sapiens (Human))
Human Biomolecular Research Institute
Curated by ChEMBL
Human Biomolecular Research Institute
Curated by ChEMBL
Affinity DataEC50: 4.5nMAssay Description:Activity at mu opioid receptor expressed in HEK293 cells assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
TargetNociceptin receptor(Homo sapiens (Human))
Human Biomolecular Research Institute
Curated by ChEMBL
Human Biomolecular Research Institute
Curated by ChEMBL
Affinity DataEC50: 94nMAssay Description:Inverse agonist activity at NOP expressed in HEK293 cells assessed as inhibition of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Homo sapiens (Human))
Human Biomolecular Research Institute
Curated by ChEMBL
Human Biomolecular Research Institute
Curated by ChEMBL
Affinity DataEC50: >1.00E+4nMAssay Description:Inverse agonist activity at kappa opioid receptor expressed in HEK293 cells assessed as inhibition of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair