BDBM50304300 CHEMBL595573::trans-N-[1-(2-fluorophenyl)-3-pyrazolyl]-3-oxospiro[6-azaisobenzofuran-1(3H),1'-cyclohexane]-4'-carboxamide
SMILES Fc1ccccc1-n1ccc(NC(=O)[C@H]2CC[C@@]3(CC2)OC(=O)c2ccncc32)n1
InChI Key InChIKey=RMYZIRFUCOMQRH-CAJLXGCNSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50304300
Affinity DataKi: 1.60nMAssay Description:Displacement of [125I]PPY from human recombinant NPYY5 receptor expressed in insect Sf9 membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 1.26nMAssay Description:Antagonistic activity at human NPY Y5 receptor expressed in HEK293 cells assessed as inhibition of calcium level by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.10nMAssay Description:Inhibition of rat Y5 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:Displacement of [125I]PYY from human recombinant Y5 receptorMore data for this Ligand-Target Pair