BDBM50304390 (cis)-4-(3,4-dimethoxyphenyl)-2-(5-((S)-3-(naphthalen-1-yloxy)-3-(thiophen-2-yl)propylamino)pentyl)-4a,5,8,8a-tetrahydrophthalazin-1(2H)-one::CHEMBL596185

SMILES COc1ccc(cc1OC)C1=NN(CCCCCNCC[C@H](Oc2cccc3ccccc23)c2cccs2)C(=O)[C@@H]2CC=CC[C@H]12

InChI Key InChIKey=QOGSMHDQGODXBS-HHMOXRITSA-N

Data  3 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50304390   

TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50304390((cis)-4-(3,4-dimethoxyphenyl)-2-(5-((S)-3-(naphtha...)
Affinity DataKi:  726nMAssay Description:Displacement of [125I]RTI-55 from human recombinant SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50304390((cis)-4-(3,4-dimethoxyphenyl)-2-(5-((S)-3-(naphtha...)
Affinity DataKi:  4.60E+3nMAssay Description:Displacement of [125I]RTI-55 from human recombinant DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50304390((cis)-4-(3,4-dimethoxyphenyl)-2-(5-((S)-3-(naphtha...)
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [125I]RTI-55 from human recombinant NET expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50304390((cis)-4-(3,4-dimethoxyphenyl)-2-(5-((S)-3-(naphtha...)
Affinity DataIC50:  6.63E+3nMAssay Description:Inhibition of [3H]DA reuptake at human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50304390((cis)-4-(3,4-dimethoxyphenyl)-2-(5-((S)-3-(naphtha...)
Affinity DataIC50:  404nMAssay Description:Inhibition of [3H]5HT reuptake at human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50304390((cis)-4-(3,4-dimethoxyphenyl)-2-(5-((S)-3-(naphtha...)
Affinity DataIC50:  2.19E+3nMAssay Description:Inhibition of [3H]NE reuptake at human NET expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed