BDBM50305420 1-(2-chlorophenyl)-5-(4-chlorophenyl)-4-(cyanomethyl)-N-(piperidin-1-yl)-1H-pyrazole-3-carboxamide::CHEMBL596163

SMILES Clc1ccc(cc1)-c1c(CC#N)c(nn1-c1ccccc1Cl)C(=O)NN1CCCCC1

InChI Key InChIKey=KBSBQWJUWFMCBI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50305420   

TargetCannabinoid receptor 1(Homo sapiens (Human))
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50305420(1-(2-chlorophenyl)-5-(4-chlorophenyl)-4-(cyanometh...)
Affinity DataIC50:  1.80nMAssay Description:Inverse agonist activity at human CB1 receptor expressed in CHO-K1 cells by GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50305420(1-(2-chlorophenyl)-5-(4-chlorophenyl)-4-(cyanometh...)
Affinity DataIC50:  7.5nMAssay Description:Antagonist activity at human recombinant CB1 receptor expressed in CHO-K1 cells assessed as inhibition of CP55940-stimulated GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50305420(1-(2-chlorophenyl)-5-(4-chlorophenyl)-4-(cyanometh...)
Affinity DataIC50:  7.5nMAssay Description:Antagonist activity at human CB1 receptor expressed in CHO-K1 cells assessed as inhibition of CP55940-induced GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed