BDBM50305541 (S)-4-{(R)-2-[1-(3-tert-Butyl-phenyl)-2-methoxy-ethylamino]-1-hydroxy-ethyl}-19-methoxymethyl-11-oxa-3,16-diaza-tricyclo[15.3.1.1*6,10*]docosa-1(21),6(22),7,9,17,19-hexaen-2-one::CHEMBL594903

SMILES COCC(NC[C@@H](O)[C@@H]1Cc2cccc(OCCCCNc3cc(COC)cc(c3)C(=O)N1)c2)c1cccc(c1)C(C)(C)C

InChI Key InChIKey=KEWIBIGKBFEKRG-DWJMSNRFSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50305541   

TargetBeta-secretase 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50305541((S)-4-{(R)-2-[1-(3-tert-Butyl-phenyl)-2-methoxy-et...)
Affinity DataIC50:  668nMAssay Description:Inhibition of human recombinant BACE1 expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed