BDBM50306496 2-(6-chloro-5-((2R,5S)-4-(1-cyano-1-(4-fluorophenyl)ethyl)-2,5-dimethylpiperazine-1-carbonyl)-1-methyl-1H-indol-3-yl)-N,N-dimethyl-2-oxoacetamide::CHEMBL601666

SMILES C[C@@H]1CN([C@@H](C)CN1C(=O)c1cc2c(cn(C)c2cc1Cl)C(=O)C(=O)N(C)C)C(C)(C#N)c1ccc(F)cc1

InChI Key InChIKey=WMPPEZSRXIQKHT-YHOPASQISA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50306496   

TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Scios

Curated by ChEMBL
LigandPNGBDBM50306496(2-(6-chloro-5-((2R,5S)-4-(1-cyano-1-(4-fluoropheny...)
Affinity DataIC50:  47nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed