BDBM50306686 CHEMBL599993::rac-3-(6-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)quinolin-3-yl)prop-2-en-1-amine

SMILES CC(Oc1ccc2ncc(\C=C\CN)cc2c1)c1c(Cl)ccc(F)c1Cl

InChI Key InChIKey=UXIHDGMIULHUSZ-NSCUHMNNSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50306686   

TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50306686(CHEMBL599993 | rac-3-(6-(1-(2,6-dichloro-3-fluorop...)
Affinity DataIC50:  4.60E+4nMAssay Description:Inhibition of recombinant Src by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50306686(CHEMBL599993 | rac-3-(6-(1-(2,6-dichloro-3-fluorop...)
Affinity DataIC50:  368nMAssay Description:Inhibition of recombinant c-Met by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50306686(CHEMBL599993 | rac-3-(6-(1-(2,6-dichloro-3-fluorop...)
Affinity DataIC50:  3.30E+4nMAssay Description:Inhibition of recombinant KDR by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed