BDBM50308733 2-Methyl-5-[4-(methylsulfonyl)phenyl]-1-[4-(methoxy)phenyl]-1H-pyrrol-3-acetic acid::CHEMBL604781

SMILES COc1ccc(cc1)-n1c(C)c(CC(O)=O)cc1-c1ccc(cc1)S(C)(=O)=O

InChI Key InChIKey=GKKGNVILYJJBKM-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50308733   

TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50308733(2-Methyl-5-[4-(methylsulfonyl)phenyl]-1-[4-(methox...)
Affinity DataIC50:  6.20E+4nMAssay Description:Inhibition of COX2-dependent PGE2 production in LPS-stimulated mouse J774 cells at 1 uM by RIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50308733(2-Methyl-5-[4-(methylsulfonyl)phenyl]-1-[4-(methox...)
Affinity DataIC50:  170nMAssay Description:Inhibition of COX2-dependent PGE2 production in LPS-stimulated mouse J774 cells by RIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Mus musculus)
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50308733(2-Methyl-5-[4-(methylsulfonyl)phenyl]-1-[4-(methox...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of COX1-dependent PGE2 production in LPS-stimulated mouse J774 cells by RIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50308733(2-Methyl-5-[4-(methylsulfonyl)phenyl]-1-[4-(methox...)
Affinity DataIC50:  9.00E+4nMAssay Description:Inhibition of COX2-dependent PGE2 production in LPS-stimulated mouse J774 cells at 10 uM by RIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed