BDBM50308735 2-Methyl-5-[4-(methylsulfonyl)phenyl]-1-[3-(fluoro)phenyl]-1H-pyrrol-3-acetic acid::CHEMBL589167

SMILES Cc1c(CC(O)=O)cc(-c2ccc(cc2)S(C)(=O)=O)n1-c1cccc(F)c1

InChI Key InChIKey=OGQTZGPSYPTJBR-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50308735   

TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50308735(2-Methyl-5-[4-(methylsulfonyl)phenyl]-1-[3-(fluoro...)
Affinity DataIC50:  8.90E+4nMAssay Description:Inhibition of COX2-dependent PGE2 production in LPS-stimulated mouse J774 cells at 1 uM by RIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50308735(2-Methyl-5-[4-(methylsulfonyl)phenyl]-1-[3-(fluoro...)
Affinity DataIC50:  9.60E+4nMAssay Description:Inhibition of COX2-dependent PGE2 production in LPS-stimulated mouse J774 cells at 10 uM by RIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50308735(2-Methyl-5-[4-(methylsulfonyl)phenyl]-1-[3-(fluoro...)
Affinity DataIC50:  28nMAssay Description:Inhibition of COX2-dependent PGE2 production in LPS-stimulated mouse J774 cells by RIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50308735(2-Methyl-5-[4-(methylsulfonyl)phenyl]-1-[3-(fluoro...)
Affinity DataIC50:  1.70E+4nMAssay Description:Inhibition of COX2 in human whole blood assessed as inhibition of LPS-induced PGE2 production by RIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Mus musculus)
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50308735(2-Methyl-5-[4-(methylsulfonyl)phenyl]-1-[3-(fluoro...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of COX1-dependent PGE2 production in LPS-stimulated mouse J774 cells by RIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50308735(2-Methyl-5-[4-(methylsulfonyl)phenyl]-1-[3-(fluoro...)
Affinity DataIC50:  1.25E+5nMAssay Description:Inhibition of COX1 in human whole blood assessed as thromboxane B2 production by RIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed