BDBM50309369 4-(5-((6,7-dichloro-1-oxo-1,2-dihydropyrrolo[1,2-a]pyrazin-4-yl)methyl)-2-fluorobenzoyl)-N,N-dimethylpiperazine-1-sulfonamide::CHEMBL597116

SMILES CN(C)S(=O)(=O)N1CCN(CC1)C(=O)c1cc(Cc2c[nH]c(=O)c3cc(Cl)c(Cl)n23)ccc1F

InChI Key InChIKey=FDIOVXDYQPWXIW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50309369   

TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Irbm/Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50309369(4-(5-((6,7-dichloro-1-oxo-1,2-dihydropyrrolo[1,2-a...)
Affinity DataIC50:  2.40nMAssay Description:Inhibition of PARP1 by topcount microplate scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed