BDBM50309548 3-(5-Bromo-1H-indol-3-yl)-4-(3,4,5-trimethoxyphenyl)-1H-pyrrole-2,5-dione::CHEMBL605957
SMILES COc1cc(cc(OC)c1OC)C1=C(C(=O)NC1=O)c1c[nH]c2ccc(Br)cc12
InChI Key InChIKey=AQXIMVWUURMKKC-UHFFFAOYSA-N
Data 10 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 10 hits for monomerid = 50309548
TargetVascular endothelial growth factor receptor 3(Homo sapiens (Human))
Hadassah Hebrew University Hospital
Curated by ChEMBL
Hadassah Hebrew University Hospital
Curated by ChEMBL
Affinity DataIC50: 21nMAssay Description:Inhibition of VEGFR3 after 80 mins by radiometric protein kinase assayMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Hadassah Hebrew University Hospital
Curated by ChEMBL
Hadassah Hebrew University Hospital
Curated by ChEMBL
Affinity DataIC50: 23nMAssay Description:Inhibition of VEGFR2 after 80 mins by radiometric protein kinase assayMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Hadassah Hebrew University Hospital
Curated by ChEMBL
Hadassah Hebrew University Hospital
Curated by ChEMBL
Affinity DataIC50: 72nMAssay Description:Inhibition of VEGFR1 after 80 mins by radiometric protein kinase assayMore data for this Ligand-Target Pair
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Hadassah Hebrew University Hospital
Curated by ChEMBL
Hadassah Hebrew University Hospital
Curated by ChEMBL
Affinity DataIC50: 2.37E+3nMAssay Description:Inhibition of TIE2 after 80 mins by radiometric protein kinase assayMore data for this Ligand-Target Pair
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Hadassah Hebrew University Hospital
Curated by ChEMBL
Hadassah Hebrew University Hospital
Curated by ChEMBL
Affinity DataIC50: 1.33E+4nMAssay Description:Inhibition of ERBB2 after 80 mins by radiometric protein kinase assayMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
Hadassah Hebrew University Hospital
Curated by ChEMBL
Hadassah Hebrew University Hospital
Curated by ChEMBL
Affinity DataIC50: 1.16E+3nMAssay Description:Inhibition of PDGFRalpha after 80 mins by radiometric protein kinase assayMore data for this Ligand-Target Pair
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Hadassah Hebrew University Hospital
Curated by ChEMBL
Hadassah Hebrew University Hospital
Curated by ChEMBL
Affinity DataIC50: 3.22E+3nMAssay Description:Inhibition of KIT after 80 mins by radiometric protein kinase assayMore data for this Ligand-Target Pair
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Hadassah Hebrew University Hospital
Curated by ChEMBL
Hadassah Hebrew University Hospital
Curated by ChEMBL
Affinity DataIC50: 4.24E+3nMAssay Description:Inhibition of IGF1R after 80 mins by radiometric protein kinase assayMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hadassah Hebrew University Hospital
Curated by ChEMBL
Hadassah Hebrew University Hospital
Curated by ChEMBL
Affinity DataIC50: 5.80E+3nMAssay Description:Inhibition of EGFR after 80 mins by radiometric protein kinase assayMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Hadassah Hebrew University Hospital
Curated by ChEMBL
Hadassah Hebrew University Hospital
Curated by ChEMBL
Affinity DataIC50: 900nMAssay Description:Inhibition of PDGFRbeta after 80 mins by radiometric protein kinase assayMore data for this Ligand-Target Pair