BDBM50309548 3-(5-Bromo-1H-indol-3-yl)-4-(3,4,5-trimethoxyphenyl)-1H-pyrrole-2,5-dione::CHEMBL605957

SMILES COc1cc(cc(OC)c1OC)C1=C(C(=O)NC1=O)c1c[nH]c2ccc(Br)cc12

InChI Key InChIKey=AQXIMVWUURMKKC-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50309548   

TargetVascular endothelial growth factor receptor 3(Homo sapiens (Human))
Hadassah Hebrew University Hospital

Curated by ChEMBL
LigandPNGBDBM50309548(3-(5-Bromo-1H-indol-3-yl)-4-(3,4,5-trimethoxypheny...)
Affinity DataIC50:  21nMAssay Description:Inhibition of VEGFR3 after 80 mins by radiometric protein kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Hadassah Hebrew University Hospital

Curated by ChEMBL
LigandPNGBDBM50309548(3-(5-Bromo-1H-indol-3-yl)-4-(3,4,5-trimethoxypheny...)
Affinity DataIC50:  23nMAssay Description:Inhibition of VEGFR2 after 80 mins by radiometric protein kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Hadassah Hebrew University Hospital

Curated by ChEMBL
LigandPNGBDBM50309548(3-(5-Bromo-1H-indol-3-yl)-4-(3,4,5-trimethoxypheny...)
Affinity DataIC50:  72nMAssay Description:Inhibition of VEGFR1 after 80 mins by radiometric protein kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Hadassah Hebrew University Hospital

Curated by ChEMBL
LigandPNGBDBM50309548(3-(5-Bromo-1H-indol-3-yl)-4-(3,4,5-trimethoxypheny...)
Affinity DataIC50:  2.37E+3nMAssay Description:Inhibition of TIE2 after 80 mins by radiometric protein kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Hadassah Hebrew University Hospital

Curated by ChEMBL
LigandPNGBDBM50309548(3-(5-Bromo-1H-indol-3-yl)-4-(3,4,5-trimethoxypheny...)
Affinity DataIC50:  1.33E+4nMAssay Description:Inhibition of ERBB2 after 80 mins by radiometric protein kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
Hadassah Hebrew University Hospital

Curated by ChEMBL
LigandPNGBDBM50309548(3-(5-Bromo-1H-indol-3-yl)-4-(3,4,5-trimethoxypheny...)
Affinity DataIC50:  1.16E+3nMAssay Description:Inhibition of PDGFRalpha after 80 mins by radiometric protein kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Hadassah Hebrew University Hospital

Curated by ChEMBL
LigandPNGBDBM50309548(3-(5-Bromo-1H-indol-3-yl)-4-(3,4,5-trimethoxypheny...)
Affinity DataIC50:  3.22E+3nMAssay Description:Inhibition of KIT after 80 mins by radiometric protein kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Hadassah Hebrew University Hospital

Curated by ChEMBL
LigandPNGBDBM50309548(3-(5-Bromo-1H-indol-3-yl)-4-(3,4,5-trimethoxypheny...)
Affinity DataIC50:  4.24E+3nMAssay Description:Inhibition of IGF1R after 80 mins by radiometric protein kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hadassah Hebrew University Hospital

Curated by ChEMBL
LigandPNGBDBM50309548(3-(5-Bromo-1H-indol-3-yl)-4-(3,4,5-trimethoxypheny...)
Affinity DataIC50:  5.80E+3nMAssay Description:Inhibition of EGFR after 80 mins by radiometric protein kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Hadassah Hebrew University Hospital

Curated by ChEMBL
LigandPNGBDBM50309548(3-(5-Bromo-1H-indol-3-yl)-4-(3,4,5-trimethoxypheny...)
Affinity DataIC50:  900nMAssay Description:Inhibition of PDGFRbeta after 80 mins by radiometric protein kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed