BDBM50310488 (R)-3-((N-(1-(3-(4-ethoxyphenyl)-4-oxo-3,4-dihydropyrido[2,3-d]pyrimidin-2-yl)ethyl)-2-(4-(trifluoromethoxy)phenyl)acetamido)methyl)pyridine 1-oxide::CHEMBL1077832
SMILES CCOc1ccc(cc1)-n1c(nc2ncccc2c1=O)[C@@H](C)N(Cc1ccc[n+]([O-])c1)C(=O)Cc1ccc(OC(F)(F)F)cc1
InChI Key InChIKey=DMBGCHREERYYSP-OAQYLSRUSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50310488
Affinity DataIC50: 4nMAssay Description:Displacement of [125I]-1P10 from human CXCR3 expressed in PBMC after 2 hrs in RPMI buffer by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Displacement of [125I]-IP-10 from CXCR3More data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Displacement of [125I]-IP-10 from CXCR3 in presence of 100% human serumMore data for this Ligand-Target Pair
Affinity DataIC50: 58nMAssay Description:Antagonist activity against human CXCR3 expressed in human PBMC assessed as inhibition of cell migration in response to ITAC in plasmaMore data for this Ligand-Target Pair