BDBM50310649 (S)-3,5-dichloro-N-isobutyl-N-(pyrrolidin-3-yl)benzamide::CHEMBL1078741

SMILES CC(C)CN([C@H]1CCNC1)C(=O)c1cc(Cl)cc(Cl)c1

InChI Key InChIKey=IECZTWNGAWLQAQ-AWEZNQCLSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50310649   

TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50310649((S)-3,5-dichloro-N-isobutyl-N-(pyrrolidin-3-yl)ben...)
Affinity DataKi:  6nMAssay Description:Displacement of [3H]5HT from human 5HT transporter expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50310649((S)-3,5-dichloro-N-isobutyl-N-(pyrrolidin-3-yl)ben...)
Affinity DataKi:  43nMAssay Description:Displacement of [3H]noradrenaline from human NET receptor expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50310649((S)-3,5-dichloro-N-isobutyl-N-(pyrrolidin-3-yl)ben...)
Affinity DataKi:  3.07E+3nMAssay Description:Displacement of [3H]dopamine from human DAT receptor expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50310649((S)-3,5-dichloro-N-isobutyl-N-(pyrrolidin-3-yl)ben...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed