BDBM50311925 CHEMBL1075628::N-(3-(1-(6-aminopyrimidin-4-yl)-1H-benzo[d]imidazol-2-ylamino)-4-methylphenyl)-1-tert-butyl-5-((4-methylpiperazin-1-yl)methyl)-1H-pyrazole-3-carboxamide
SMILES CN1CCN(Cc2cc(nn2C(C)(C)C)C(=O)Nc2ccc(C)c(Nc3nc4ccccc4n3-c3cc(N)ncn3)c2)CC1
InChI Key InChIKey=PPCDZYRDXIKRDW-UHFFFAOYSA-N
Data 8 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 50311925
TargetTyrosine-protein kinase Lck(Human)
Genomics Institute of The Novartis Research Foundation
Curated by ChEMBL
Genomics Institute of The Novartis Research Foundation
Curated by ChEMBL
TargetInsulin receptor(Human)
Genomics Institute of The Novartis Research Foundation
Curated by ChEMBL
Genomics Institute of The Novartis Research Foundation
Curated by ChEMBL
Affinity DataIC50: 818nMAssay Description:Inhibition of Tel-fused InsR expressed in mouse BAF3 cellsMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Genomics Institute of The Novartis Research Foundation
Curated by ChEMBL
Genomics Institute of The Novartis Research Foundation
Curated by ChEMBL
TargetTyrosine-protein kinase HCK(Human)
Genomics Institute of The Novartis Research Foundation
Curated by ChEMBL
Genomics Institute of The Novartis Research Foundation
Curated by ChEMBL
TargetTyrosine-protein kinase Lyn(Human)
Genomics Institute of The Novartis Research Foundation
Curated by ChEMBL
Genomics Institute of The Novartis Research Foundation
Curated by ChEMBL
Affinity DataIC50: 88nMAssay Description:Inhibition of Tel-fused LYN expressed in mouse BAF3 cellsMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Genomics Institute of The Novartis Research Foundation
Curated by ChEMBL
Genomics Institute of The Novartis Research Foundation
Curated by ChEMBL
Affinity DataIC50: 249nMAssay Description:Inhibition of Tel-fused SRC expressed in mouse BAF3 cellsMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Human)
Genomics Institute of The Novartis Research Foundation
Curated by ChEMBL
Genomics Institute of The Novartis Research Foundation
Curated by ChEMBL
Affinity DataIC50: 63nMAssay Description:Inhibition of Tel-fused KDR expressed in mouse BAF3 cellsMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase Lck(Human)
Genomics Institute of The Novartis Research Foundation
Curated by ChEMBL
Genomics Institute of The Novartis Research Foundation
Curated by ChEMBL
Affinity DataIC50: 18nMAssay Description:Inhibition of Tel-fused LCK expressed in mouse BAF3 cellsMore data for this Ligand-Target Pair