BDBM50311985 3-(7-(4-((1S,4S)-5-methyl-2,5-diazabicyclo[2.2.1]heptan-2-yl)phenyl)-2-(pyridin-4-yl)pyrazolo[1,5-a]pyrimidin-3-yl)phenol::CHEMBL1087650
SMILES CN1C[C@@H]2C[C@H]1CN2c1ccc(cc1)-c1ccnc2c(c(nn12)-c1ccncc1)-c1cccc(O)c1
InChI Key InChIKey=MZPDPRITYJNRSG-ZEQRLZLVSA-N
Data 24 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 24 hits for monomerid = 50311985
Affinity DataIC50: 2.46E+3nMAssay Description:Inhibition of PKCalphaMore data for this Ligand-Target Pair
Affinity DataIC50: 2.55E+4nMAssay Description:Inhibition of Aurora BMore data for this Ligand-Target Pair
Affinity DataIC50: 2.84E+4nMAssay Description:Inhibition of CDK1More data for this Ligand-Target Pair
Affinity DataIC50: 1.86E+4nMAssay Description:Inhibition of CHK1More data for this Ligand-Target Pair
Affinity DataIC50: 0.380nMAssay Description:Inhibition of human recombinant B-Raf expressed in Sf9 cells assessed as inhibition of Mek1 phosphorylationMore data for this Ligand-Target Pair
Affinity DataIC50: 2.64E+4nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
Affinity DataIC50: 9.51E+3nMAssay Description:Inhibition of CK1gamma1More data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of ERK2More data for this Ligand-Target Pair
Affinity DataIC50: 1.94E+3nMAssay Description:Inhibition of FYNMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase kinase 2(Homo sapiens (Human))
Wyeth Research
Curated by ChEMBL
Wyeth Research
Curated by ChEMBL
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of GCKMore data for this Ligand-Target Pair
Affinity DataIC50: 1.24E+3nMAssay Description:Inhibition of HCKMore data for this Ligand-Target Pair
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
Wyeth Research
Curated by ChEMBL
Wyeth Research
Curated by ChEMBL
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of IKK-betaMore data for this Ligand-Target Pair
Affinity DataIC50: 1.76E+3nMAssay Description:Inhibition of LYNMore data for this Ligand-Target Pair
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of MetMore data for this Ligand-Target Pair
Affinity DataIC50: 1.71E+4nMAssay Description:Inhibition of MK2More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
Wyeth Research
Curated by ChEMBL
Wyeth Research
Curated by ChEMBL
Affinity DataIC50: 6.56E+3nMAssay Description:Inhibition of PDGFRalphaMore data for this Ligand-Target Pair
Affinity DataIC50: 119nMAssay Description:Inhibition of PKCbetaMore data for this Ligand-Target Pair
Affinity DataIC50: 1.76E+4nMAssay Description:Inhibition of ROCK1More data for this Ligand-Target Pair
Affinity DataIC50: 9.71E+3nMAssay Description:Inhibition of RSk1More data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research
Curated by ChEMBL
Wyeth Research
Curated by ChEMBL
Affinity DataIC50: 69nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
TargetInhibitor of nuclear factor kappa-B kinase subunit alpha(Homo sapiens (Human))
Wyeth Research
Curated by ChEMBL
Wyeth Research
Curated by ChEMBL
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of IKKalphaMore data for this Ligand-Target Pair