BDBM50312289 4-(((2S,4R)-1-benzoyl-2-methyl-1,2,3,4-tetrahydroquinolin-4-yl)(phenyl)amino)-4-oxobutanoic acid::CHEMBL1080199

SMILES C[C@H]1C[C@@H](N(C(=O)CCC(O)=O)c2ccccc2)c2ccccc2N1C(=O)c1ccccc1

InChI Key InChIKey=SKMCUINBBWXWBC-YADARESESA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50312289   

TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50312289(4-(((2S,4R)-1-benzoyl-2-methyl-1,2,3,4-tetrahydroq...)
Affinity DataIC50:  130nMAssay Description:Displacement of [3H]PGD2 from human CRTH2 receptor expressed in 293 cells by scintillation counting in presence of 50% human plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50312289(4-(((2S,4R)-1-benzoyl-2-methyl-1,2,3,4-tetrahydroq...)
Affinity DataIC50:  3nMAssay Description:Displacement of [3H]PGD2 from human CRTH2 receptor expressed in 293 cells by scintillation counting in presence of 0.5% BSAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50312289(4-(((2S,4R)-1-benzoyl-2-methyl-1,2,3,4-tetrahydroq...)
Affinity DataIC50:  3nMAssay Description:Inhibition of CRTH2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50312289(4-(((2S,4R)-1-benzoyl-2-methyl-1,2,3,4-tetrahydroq...)
Affinity DataIC50:  0.770nMAssay Description:Inhibition of CRTH2 in human whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50312289(4-(((2S,4R)-1-benzoyl-2-methyl-1,2,3,4-tetrahydroq...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [3H]PGD2 from human DP receptor expressed in 293 cells by scintillation counting in presence of 0.5% BSAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed