BDBM50312923 (S)-N1-(2-(isoquinolin-6-yl)thiazol-5-yl)-3-(4-(trifluoromethyl)phenyl)propane-1,2-diamine::CHEMBL1081425

SMILES N[C@H](CNc1cnc(s1)-c1ccc2cnccc2c1)Cc1ccc(cc1)C(F)(F)F

InChI Key InChIKey=YZANFKNGZATACL-IBGZPJMESA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50312923   

TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50312923((S)-N1-(2-(isoquinolin-6-yl)thiazol-5-yl)-3-(4-(tr...)
Affinity DataIC50:  1.07E+3nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50312923((S)-N1-(2-(isoquinolin-6-yl)thiazol-5-yl)-3-(4-(tr...)
Affinity DataIC50:  404nMAssay Description:Inhibition of human AKT1 in human U87MG cells assessed as PRAS40 phosphorylation after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed