BDBM50312927 (S)-N1-(5-(1H-indazol-6-yl)thiazol-2-yl)-3-(4-(trifluoromethyl)phenyl)propane-1,2-diamine::CHEMBL1079625

SMILES N[C@H](CNc1ncc(s1)-c1ccc2cn[nH]c2c1)Cc1ccc(cc1)C(F)(F)F

InChI Key InChIKey=SXMJEDMPDDTFKV-INIZCTEOSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50312927   

TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50312927((S)-N1-(5-(1H-indazol-6-yl)thiazol-2-yl)-3-(4-(tri...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50312927((S)-N1-(5-(1H-indazol-6-yl)thiazol-2-yl)-3-(4-(tri...)
Affinity DataIC50:  613nMAssay Description:Inhibition of human AKT1 in human U87MG cells assessed as PRAS40 phosphorylation after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed