BDBM50312928 (S)-N1-(5-(1-methyl-1H-indazol-6-yl)thiazol-2-yl)-3-(4-(trifluoromethyl)phenyl)propane-1,2-diamine::CHEMBL1079626

SMILES Cn1ncc2ccc(cc12)-c1cnc(NC[C@@H](N)Cc2ccc(cc2)C(F)(F)F)s1

InChI Key InChIKey=GFKUTFHFJROQLY-KRWDZBQOSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50312928   

TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50312928((S)-N1-(5-(1-methyl-1H-indazol-6-yl)thiazol-2-yl)-...)
Affinity DataIC50:  895nMAssay Description:Inhibition of human AKT1 in human U87MG cells assessed as PRAS40 phosphorylation after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed