BDBM50313150 8-amino-2,7-diisobutyl-4-isopentyl-4,5-dihydro-1H-benzo[e][1,4]diazepin-3(2H)-one::CHEMBL1087253
SMILES CC(C)CCN1Cc2cc(CC(C)C)c(N)cc2N[C@@H](CC(C)C)C1=O
InChI Key InChIKey=DAWHMMINFGNTOI-NRFANRHFSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50313150
Affinity DataIC50: 3.00E+4nMAssay Description:Displacement of 1,25-dihydroxyvitamin D3 from GST-tagged VDR ligand binding domain assessed as inhibition of interaction with coactivator proteins by...More data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+4nMAssay Description:Antagonist activity at human recombinant VDR LBD expressed in HEK293 cells assessed as inhibition of 3 nM 1,25-(OH)2D3-induced transcriptional activa...More data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+4nMAssay Description:Antagonist activity at human recombinant ERalpha LBD expressed in HEK293 cells assessed as inhibition of 0.3 nM estradiol-induced transcriptional act...More data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+4nMAssay Description:Antagonist activity at human recombinant VDR LBD expressed in HEK293 cells assessed as inhibition of 300 nM 1,25-(OH)2D3-induced transcriptional acti...More data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+4nMAssay Description:Antagonist activity at human recombinant ERbeta LBD expressed in HEK293 cells assessed as inhibition of 0.3 nM estradiol-induced transcriptional acti...More data for this Ligand-Target Pair