BDBM50313469 4-(3-(methylsulfonyl)phenyl)-6-propylpyrimidine-2-carbonitrile::CHEMBL1082858

SMILES CCCc1cc(nc(n1)C#N)-c1cccc(c1)S(C)(=O)=O

InChI Key InChIKey=UXVCQUAZYFJMPX-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50313469   

TargetCathepsin K(Homo sapiens (Human))
Schering-Plough

Curated by ChEMBL
LigandPNGBDBM50313469(4-(3-(methylsulfonyl)phenyl)-6-propylpyrimidine-2-...)
Affinity DataIC50:  148nMAssay Description:Inhibition of human recombinant cathepsin K by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Schering-Plough

Curated by ChEMBL
LigandPNGBDBM50313469(4-(3-(methylsulfonyl)phenyl)-6-propylpyrimidine-2-...)
Affinity DataIC50:  93nMAssay Description:Inhibition of human recombinant cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Schering-Plough

Curated by ChEMBL
LigandPNGBDBM50313469(4-(3-(methylsulfonyl)phenyl)-6-propylpyrimidine-2-...)
Affinity DataIC50:  148nMAssay Description:Inhibition of human recombinant cathepsin KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Schering-Plough

Curated by ChEMBL
LigandPNGBDBM50313469(4-(3-(methylsulfonyl)phenyl)-6-propylpyrimidine-2-...)
Affinity DataIC50:  93nMAssay Description:Inhibition of human recombinant cathepsin SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50313469(4-(3-(methylsulfonyl)phenyl)-6-propylpyrimidine-2-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant cathepsin BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50313469(4-(3-(methylsulfonyl)phenyl)-6-propylpyrimidine-2-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant cathepsin LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed