BDBM50313604 5'-Fluoro-1H,1'H-[2,3']biindolylidene-3,2'-dione 3-oxime::CHEMBL1077291

SMILES Fc1ccc2NC(=O)C(c2c1)c1[nH]c2ccccc2c1N=O

InChI Key InChIKey=XEIDGVAXPPRCTD-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50313604   

TargetSerine/threonine-protein kinase 17B(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50313604(5'-Fluoro-1H,1'H-[2,3']biindolylidene-3,2'-dione 3...)
Affinity DataIC50:  620nMAssay Description:Inhibition of DRAK2 (unknown origin) using MRLC3 peptide as substrate incubated for 2 hrs by ADP-Glo kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50313604(5'-Fluoro-1H,1'H-[2,3']biindolylidene-3,2'-dione 3...)
Affinity DataIC50:  1.27E+3nMAssay Description:Inhibition of Aurora A by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin receptor(Homo sapiens (Human))
Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50313604(5'-Fluoro-1H,1'H-[2,3']biindolylidene-3,2'-dione 3...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of insulin receptor by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50313604(5'-Fluoro-1H,1'H-[2,3']biindolylidene-3,2'-dione 3...)
Affinity DataIC50:  15nMAssay Description:Inhibition of FLT3 by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage-stimulating protein receptor(Homo sapiens (Human))
Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50313604(5'-Fluoro-1H,1'H-[2,3']biindolylidene-3,2'-dione 3...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Ron by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50313604(5'-Fluoro-1H,1'H-[2,3']biindolylidene-3,2'-dione 3...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Met by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50313604(5'-Fluoro-1H,1'H-[2,3']biindolylidene-3,2'-dione 3...)
Affinity DataIC50:  1.53E+3nMAssay Description:Inhibition of VEGFR2 by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50313604(5'-Fluoro-1H,1'H-[2,3']biindolylidene-3,2'-dione 3...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of EGFR by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed