BDBM50314032 (2S,5S,8S,11S,14S,17S,20S)-17-((1H-imidazol-5-yl)methyl)-20-amino-11-(2-cyclohexylethyl)-2-(3-guanidinopropyl)-21-hydroxy-8,14-diisobutyl-5-methyl-4,7,10,13,16,19-hexaoxo-3,6,9,12,15,18-hexaazahenicosan-1-oic acid::CHEMBL1089592

SMILES CC(C)C[C@H](NC(=O)[C@H](CCC1CCCCC1)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@@H](N)CO)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCN=C(N)N)C(O)=O

InChI Key InChIKey=JCYQBFQTKHGSPK-VDXNIVNJSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50314032   

TargetComplement factor B(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50314032((2S,5S,8S,11S,14S,17S,20S)-17-((1H-imidazol-5-yl)m...)
Affinity DataIC50:  5.00E+3nMpH: 9.5Assay Description:Inhibition of human complement factor B treated for 5 mins before addition of substrate Ac-SHLGLAR-pNA at pH 9.5 by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed