BDBM50314228 (R)-N-hydroxy-2-(N-isobutyl-4-methoxyphenylsulfonamido)-3-methylbutanamide::CHEMBL1090284
SMILES COc1ccc(cc1)S(=O)(=O)N(CC(C)C)[C@H](C(C)C)C(=O)NO
InChI Key InChIKey=KLOYCYLPVRADHA-OAHLLOKOSA-N
Data 9 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 50314228
Affinity DataIC50: 7.20nMAssay Description:Inhibition of MMP9 by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Inhibition of human recombinant MMP14 by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 7.20nMAssay Description:Inhibition of recombinant human MMP9 after 2 hrs using FS-6 as substrate by fluorometryMore data for this Ligand-Target Pair
Target72 kDa type IV collagenase(Homo sapiens (Human))
Uit The Arctic University Of Norway
Curated by ChEMBL
Uit The Arctic University Of Norway
Curated by ChEMBL
Affinity DataIC50: 29nMAssay Description:Inhibition of recombinant human MMP2 after 2 hrs using FS-6 as substrate by fluorometryMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human recombinant ADAM17 by fluorometric assayMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of recombinant human ADAM17 after 30 mins using FS-6 as substrate by fluorometryMore data for this Ligand-Target Pair
Affinity DataIC50: 56nMAssay Description:Inhibition of MMP1 by fluorometric assayMore data for this Ligand-Target Pair
Target72 kDa type IV collagenase(Homo sapiens (Human))
Uit The Arctic University Of Norway
Curated by ChEMBL
Uit The Arctic University Of Norway
Curated by ChEMBL
Affinity DataIC50: 29nMAssay Description:Inhibition of MMP2 by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.03E+5nMAssay Description:Inhibition of Bacillus thermoproteolyticus pseudolysin pretreated with compound for 15 mins followed by the addition of Abz-Ala-Gly-leu-Ala-p-nitrobe...More data for this Ligand-Target Pair