BDBM50314766 CHEMBL1093306::trans-N-(2-((R)-1'-((3R,4S)-1-tert-butyl-4-(2,4-difluorophenyl)pyrrolidine-3-carbonyl)-6-chloro-5-methyl-2,3-dihydrospiro[indene-1,4'-piperidine]-3-yl)propan-2-yl)acetamide

SMILES CC(=O)NC(C)(C)[C@@H]1CC2(CCN(CC2)C(=O)[C@H]2CN(C[C@@H]2c2ccc(F)cc2F)C(C)(C)C)c2cc(Cl)c(C)cc12

InChI Key InChIKey=KMNARKQYUZICHM-FULLSBAXSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50314766   

TargetMelanocortin receptor 4(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50314766(CHEMBL1093306 | trans-N-(2-((R)-1'-((3R,4S)-1-tert...)
Affinity DataIC50:  89nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC4R expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50314766(CHEMBL1093306 | trans-N-(2-((R)-1'-((3R,4S)-1-tert...)
Affinity DataEC50:  94nMAssay Description:Agonist activity at human MC4R expressed in CHO cells assessed as stimulation of intracellular cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed