BDBM50314789 CHEMBL1088796::N-cyclopropyl-3-(1-(2-fluorophenyl)phthalazin-6-yl)-4-methylbenzamide

SMILES Cc1ccc(cc1-c1ccc2c(nncc2c1)-c1ccccc1F)C(=O)NC1CC1

InChI Key InChIKey=WAKUIUNRDNSMQR-UHFFFAOYSA-N

Data  4 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50314789   

TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50314789(CHEMBL1088796 | N-cyclopropyl-3-(1-(2-fluorophenyl...)
Affinity DataKd:  0.0500nMAssay Description:Binding affinity to p38alpha by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50314789(CHEMBL1088796 | N-cyclopropyl-3-(1-(2-fluorophenyl...)
Affinity DataKd:  2.40nMAssay Description:Binding affinity to c-Kit by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50314789(CHEMBL1088796 | N-cyclopropyl-3-(1-(2-fluorophenyl...)
Affinity DataKd:  530nMAssay Description:Binding affinity to Lck by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50314789(CHEMBL1088796 | N-cyclopropyl-3-(1-(2-fluorophenyl...)
Affinity DataKd:  320nMAssay Description:Binding affinity to Kdr by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed