BDBM50314844 3'-Deoxy-3'-(4-phenyl-1,2,3-triazol-1-yl)-beta-(E)-5-(2-bromovinyl)-2'-deoxyuridine::CHEMBL1091931
SMILES OC[C@H]1O[C@H](C[C@@H]1n1cc(nn1)-c1ccccc1)n1cc(C=CBr)c(=O)[nH]c1=O
InChI Key InChIKey=DMKMKCDASKTBRN-GVDBMIGSSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50314844
Affinity DataIC50: 250nMAssay Description:Inhibition of human recombinant mitochondrial thymidine kinase 2 assessed as inhibition of [methyl-3H]dThd phosphorylation after 30 mins by scintilla...More data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of human recombinant cytosolic thymidine kinase 1 assessed as inhibition of [methyl-3H]dThd phosphorylation after 30 mins by scintillation...More data for this Ligand-Target Pair
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of Drosophila melanogaster multifunctional deoxynucleoside kinase assessed as inhibition of [methyl-3H]dThd phosphorylation after 30 mins ...More data for this Ligand-Target Pair
TargetThymidine kinase(Human herpesvirus 1 (strain SC16) (HHV-1) (Human h...)
Ghent University
Curated by ChEMBL
Ghent University
Curated by ChEMBL
Affinity DataIC50: 3.60E+4nMAssay Description:Inhibition of HSV1 thymidine kinase assessed as inhibition of [methyl-3H]dThd phosphorylation after 30 mins by scintillation countingMore data for this Ligand-Target Pair