BDBM50315562 (R)-2-amino-2-(4-(4-(biphenyl-4-ylmethoxy)-3-(trifluoromethyl)phenyl)-1H-imidazol-2-yl)propyl dihydrogen phosphate::CHEMBL1093823
SMILES C[C@](N)(COP(O)(O)=O)c1nc(c[nH]1)-c1ccc(OCc2ccc(cc2)-c2ccccc2)c(c1)C(F)(F)F
InChI Key InChIKey=LXNKUNKMYYJPKD-VWLOTQADSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50315562
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Praecis Pharmaceuticals
Curated by ChEMBL
Praecis Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 0.230nMAssay Description:Displacement of [33P]sphingosine-1-phosphate from human S1P1 receptor expressed in HEK293T cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
Praecis Pharmaceuticals
Curated by ChEMBL
Praecis Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 2.00E+3nMAssay Description:Displacement of [33P]sphingosine-1-phosphate from human S1P3 receptor expressed in HEK293T cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
Praecis Pharmaceuticals
Curated by ChEMBL
Praecis Pharmaceuticals
Curated by ChEMBL
Affinity DataEC50: >3.00E+3nMAssay Description:Antagonist activity at human S1P3 receptor expressed in HEK293T cells assessed as inhibition of sphingosine-1-phosphate-induced gamma-[35S]GTP bindin...More data for this Ligand-Target Pair
TargetSphingosine 1-phosphate receptor 5(Homo sapiens (Human))
Praecis Pharmaceuticals
Curated by ChEMBL
Praecis Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 9.60nMAssay Description:Displacement of [33P]sphingosine-1-phosphate from human S1P5 receptor expressed in HEK293T cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Praecis Pharmaceuticals
Curated by ChEMBL
Praecis Pharmaceuticals
Curated by ChEMBL
Affinity DataEC50: 1.62nMAssay Description:Antagonist activity at human S1P1 receptor expressed in HEK293T cells assessed as inhibition of sphingosine-1-phosphate-induced gamma-[35S]GTP bindin...More data for this Ligand-Target Pair
TargetSphingosine 1-phosphate receptor 4(Homo sapiens (Human))
Praecis Pharmaceuticals
Curated by ChEMBL
Praecis Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 4.40nMAssay Description:Displacement of [33P]sphingosine-1-phosphate from human S1P4 receptor expressed in HEK293T cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair