BDBM50315664 2-(4-chloro-6-(isopentylamino)pyrimidin-2-ylthio)-2-(naphthalen-1-yl)acetic acid::CHEMBL1089317

SMILES CC(C)CCNc1cc(Cl)nc(SC(C(O)=O)c2cccc3ccccc23)n1

InChI Key InChIKey=COUZGLSEBNURHL-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50315664   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50315664(2-(4-chloro-6-(isopentylamino)pyrimidin-2-ylthio)-...)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of 5-lipoxygenase in human PMNLMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50315664(2-(4-chloro-6-(isopentylamino)pyrimidin-2-ylthio)-...)
Affinity DataEC50:  8.90E+3nMAssay Description:Transactivation of human PPARgamma LBD expressed in african green monkey Cos7 cells co-transfected with fused GAL4-DBD after 14 hrs by Dual-Glo Lucif...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed