BDBM50315666 2-(4-chloro-6-(3-phenylpropylamino)pyrimidin-2-ylthio)-2-(naphthalen-1-yl)acetic acid::CHEMBL1089826
SMILES OC(=O)C(Sc1nc(Cl)cc(NCCCc2ccccc2)n1)c1cccc2ccccc12
InChI Key InChIKey=MTEBXMPXGZSGGW-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50315666
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Goethe-University Frankfurt
Curated by ChEMBL
Goethe-University Frankfurt
Curated by ChEMBL
Affinity DataEC50: 8.90E+3nMAssay Description:Transactivation of human PPARgamma LBD expressed in african green monkey Cos7 cells co-transfected with fused GAL4-DBD after 14 hrs by Dual-Glo Lucif...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Goethe-University Frankfurt
Curated by ChEMBL
Goethe-University Frankfurt
Curated by ChEMBL
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of 5-lipoxygenase in human PMNLMore data for this Ligand-Target Pair
Affinity DataIC50: 6.10E+3nMAssay Description:Inhibition of mPGES-1 expressed in LPS-stimulated human A549 cells mitochondrial fraction assessed as conversion of PGH2 to PGE2More data for this Ligand-Target Pair