BDBM50315776 1-(3-(5-chloro-4-(1-methyl-1H-pyrazol-4-yl)-1H-pyrrolo[2,3-b]pyridin-2-yl)phenyl)-N,N-dimethylmethanamine::CHEMBL587029::TCMDC-134147

SMILES CN(C)Cc1cccc(c1)-c1cc2c(-c3cnn(C)c3)c(Cl)cnc2[nH]1

InChI Key InChIKey=ULOLUGXMKLIZGE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50315776   

TargetAurora kinase B(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50315776(1-(3-(5-chloro-4-(1-methyl-1H-pyrazol-4-yl)-1H-pyr...)
Affinity DataIC50:  67nMAssay Description:Inhibition of aurora B assessed as inhibition of histone H3 phosphorylation by ELISA based cellular mechanistic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed