BDBM50316118 6-Allylamino-2-allylthio-3-benzyl-quinazolin-4(3H)-one::CHEMBL1092683

SMILES C=CCNc1ccc2nc(SCC=C)n(Cc3ccccc3)c(=O)c2c1

InChI Key InChIKey=HORCLIXLGRGPLS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50316118   

TargetDihydrofolate reductase(Bos taurus (Cattle))
King Saud University

Curated by ChEMBL
LigandPNGBDBM50316118(6-Allylamino-2-allylthio-3-benzyl-quinazolin-4(3H)...)
Affinity DataIC50:  800nMAssay Description:Inhibition of bovine DHFR after 2 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
King Saud University

Curated by ChEMBL
LigandPNGBDBM50316118(6-Allylamino-2-allylthio-3-benzyl-quinazolin-4(3H)...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of human DHFR after 2 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed