BDBM50316122 CHEMBL1093519::N-(2-Allylthio-3-benzyl-4-oxo-3,4-dihydro-quinazolin-6-yl)-cinnamamide

SMILES C=CCSc1nc2ccc(NC(=O)\C=C\c3ccccc3)cc2c(=O)n1Cc1ccccc1

InChI Key InChIKey=YTGKMTUROACZQB-DTQAZKPQSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50316122   

TargetDihydrofolate reductase(Bos taurus (Cattle))
King Saud University

Curated by ChEMBL
LigandPNGBDBM50316122(CHEMBL1093519 | N-(2-Allylthio-3-benzyl-4-oxo-3,4-...)
Affinity DataIC50:  700nMAssay Description:Inhibition of bovine DHFR after 2 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
King Saud University

Curated by ChEMBL
LigandPNGBDBM50316122(CHEMBL1093519 | N-(2-Allylthio-3-benzyl-4-oxo-3,4-...)
Affinity DataIC50:  500nMAssay Description:Inhibition of human DHFR after 2 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed