BDBM50316124 (E)-N-(3-Benzyl-2-cinnamylthio-4-oxo-3,4-dihydroquinazolin-6-yl)-acryl-amide::CHEMBL1093243

SMILES C=CC(=O)Nc1ccc2nc(SC\C=C\c3ccccc3)n(Cc3ccccc3)c(=O)c2c1

InChI Key InChIKey=HTFVOUCBMVLKAU-NTEUORMPSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50316124   

TargetDihydrofolate reductase(Bos taurus (Cattle))
King Saud University

Curated by ChEMBL
LigandPNGBDBM50316124((E)-N-(3-Benzyl-2-cinnamylthio-4-oxo-3,4-dihydroqu...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of bovine DHFR after 2 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
King Saud University

Curated by ChEMBL
LigandPNGBDBM50316124((E)-N-(3-Benzyl-2-cinnamylthio-4-oxo-3,4-dihydroqu...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of human DHFR after 2 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed