BDBM50316236 2-(4-{[(2,2-Difluoroethyl)amino]methyl}phenyl)-2H-indazole-7-carboxamide::CHEMBL1094958

SMILES NC(=O)c1cccc2cn(nc12)-c1ccc(CNCC(F)F)cc1

InChI Key InChIKey=ZJQXJILIJAEYNO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50316236   

TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Irbm/Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50316236(2-(4-{[(2,2-Difluoroethyl)amino]methyl}phenyl)-2H-...)
Affinity DataIC50:  14nMAssay Description:Inhibition of human PARP1 by SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed