BDBM50316378 1,1'-(1,3,7,9-Tetrahydroxydibenzofuran-2,6-diyl)bis(3-methylbutan-1-one)::CHEMBL1097226::US9273021, 3

SMILES CC(C)CC(=O)c1c(O)cc2oc3c(C(=O)CC(C)C)c(O)cc(O)c3c2c1O

InChI Key InChIKey=NSJHIYMKOLGKSR-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50316378   

TargetFructose-1,6-bisphosphatase 1(Sus scrofa (Pig))
Boston College

US Patent
LigandPNGBDBM50316378(1,1'-(1,3,7,9-Tetrahydroxydibenzofuran-2,6-diyl)bi...)
Affinity DataIC50:  1.50E+3nMpH: 7.5Assay Description:FBPase activity was measured spectrophotometrically by employing the coupling enzymes phosphoglucose isomerase and glucose-6-phosphate dehydrogenase....More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFructose-1,6-bisphosphatase 1(Sus scrofa (Pig))
Boston College

US Patent
LigandPNGBDBM50316378(1,1'-(1,3,7,9-Tetrahydroxydibenzofuran-2,6-diyl)bi...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of pig kidney fructose-1,6-bisphosphatase expressed in Escherichia coli BL21 (DE3) assessed as reduction of NADP+ to NADPH by phosphogluco...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFructose-1,6-bisphosphatase 1(Homo sapiens (Human))
Boston College

Curated by ChEMBL
LigandPNGBDBM50316378(1,1'-(1,3,7,9-Tetrahydroxydibenzofuran-2,6-diyl)bi...)
Affinity DataIC50:  8.10E+3nMAssay Description:Inhibition of human liver fructose-1,6-bisphosphatase expressed in Escherichia coli BL21 (DE3) assessed as reduction of NADP+ to NADPH by phosphogluc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFructose-1,6-bisphosphatase 1(Homo sapiens (Human))
Boston College

Curated by ChEMBL
LigandPNGBDBM50316378(1,1'-(1,3,7,9-Tetrahydroxydibenzofuran-2,6-diyl)bi...)
Affinity DataIC50:  8.10E+3nMpH: 7.5Assay Description:FBPase activity was measured spectrophotometrically by employing the coupling enzymes phosphoglucose isomerase and glucose-6-phosphate dehydrogenase....More data for this Ligand-Target Pair
In DepthDetails US Patent